The Science โ€” Peak Wild Supplements
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Wild Ingredients. Real Research.

We don't hide behind buzzwords. Every core ingredient in the Peak Wild collection is backed by peer-reviewed human and preclinical research โ€” and we link every source, so you can read the studies yourself.

36Peer-Reviewed Studies
14Core Ingredients
100%Sources Linked

๐Ÿ„ Lion's Mane Mushroom โ€” Hericium erinaceus

In: Mushroom Extract Complex โ†’

Lion's Mane contains hericenones and erinacines โ€” compounds that stimulate Nerve Growth Factor (NGF) synthesis in the brain. Multiple human clinical trials show improvements in mild cognitive impairment, focus, and memory.

Phytotherapy Research ยท 2009 ยท Mori K, et al.

Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment

Subjects taking Lion's Mane for 16 weeks showed significantly higher cognitive function scores vs placebo. Scores declined after discontinuation.

Read on PubMed โ†’
International Journal of Medicinal Mushrooms · 2013 · Lai PL, et al.

Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus, from Malaysia

Lion's Mane extracts demonstrated neurotrophic activity, stimulating neurite outgrowth — the mechanism behind its nerve-growth-factor reputation.

Read on PubMed →
Biomedical Research · 2010 · Nagano M, et al.

Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake

Participants consuming Lion's Mane for 4 weeks reported significantly reduced depression and anxiety scores compared with the placebo group.

Read on PubMed →

โ›ฐ๏ธ Shilajit โ€” Asphaltum punjabianum

In: Shilajit Adaptogen Complex โ†’

Shilajit is a rare mineral resin formed over centuries in Himalayan rock. Clinical research links its fulvic acid and 80+ trace minerals to improved energy metabolism, testosterone support, and performance at altitude.

International Journal of Ayurveda Research · 2010 · Meena H, et al.

Shilajit: A panacea for high-altitude problems

A review of Shilajit's constituents and traditional use at altitude, covering fatigue, hypoxia tolerance and energy metabolism.

Read on PubMed →
Andrologia · 2016 · Pandit S, et al.

Clinical evaluation of purified Shilajit on testosterone levels in healthy volunteers

In a 90-day randomised, double-blind, placebo-controlled trial, healthy volunteers aged 45–55 taking purified Shilajit showed significantly higher total and free testosterone than placebo.

Read on PubMed →
Journal of Ethnopharmacology · 2012 · Surapaneni DK, et al.

Shilajit attenuates behavioral symptoms of chronic fatigue syndrome by modulating the HPA axis and mitochondrial bioenergetics

Shilajit modulated the hypothalamic-pituitary-adrenal axis and mitochondrial bioenergetics, easing behavioural symptoms in an experimental model of chronic fatigue.

Read on PubMed →

๐Ÿ’ง Methylene Blue โ€” Methylthioninium chloride

In: Methylene Blue Drops โ†’

Methylene Blue is a mitochondrial electron carrier with over 150 years of pharmaceutical use. Modern research shows it acts as an alternative electron acceptor in the mitochondrial electron transport chain, enhancing ATP production and cognitive performance.

Pharmacology Biochemistry and Behavior · 2004 · Callaway NL, et al.

Methylene blue improves brain oxidative metabolism and memory retention in rats

A single low dose of methylene blue raised brain cytochrome oxidase activity and improved memory retention in rats — the foundational animal work behind its metabolic-enhancer reputation.

Read on PubMed →
Progress in Neurobiology · 2012 · Rojas JC, et al.

Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue

A review of how low-dose methylene blue enhances mitochondrial respiration, and the neurometabolic basis for its memory and neuroprotective effects.

Read on PubMed →
Biochemical Pharmacology · 2014 · Gonzalez-Lima F, et al.

Mitochondrial respiration as a target for neuroprotection and cognitive enhancement

Reviews mitochondrial respiration as a therapeutic target, with low-dose methylene blue as the lead metabolic enhancer for cognition and neuroprotection.

Read on PubMed →

โšก Creatine Monohydrate โ€” Creatine Monohydrate + HCl

In: Creatine Hydration Powder โ†’

Creatine is the most researched supplement in sports science history with over 500 peer-reviewed studies. It increases phosphocreatine stores in muscle, enabling faster ATP regeneration for explosive strength, power output, and cognitive function.

Journal of Strength and Conditioning Research ยท 2003 ยท Rawson ES & Volek JS

Effects of creatine supplementation on exercise performance

Meta-analysis of 22 studies: creatine supplementation produced an average 8% increase in strength and 14% increase in power output.

Read on PubMed โ†’
Neuropsychology, Development, and Cognition ยท 2007 ยท McMorris T, et al.

Creatine supplementation and cognitive performance in elderly individuals

Older adults supplementing with creatine showed significant improvements in working memory and intelligence test scores.

Read on PubMed โ†’
Journal of the International Society of Sports Nutrition · 2017 · Kreider RB, et al.

International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine

Comprehensive review confirms creatine is the most effective ergogenic nutritional supplement for increasing high-intensity exercise capacity and lean body mass.

Read on PubMed →

๐ŸŒณ Tongkat Ali โ€” Eurycoma longifolia

In: Shilajit Adaptogen Complex โ†’

Tongkat Ali is a Southeast Asian root studied for hormonal health and stress resilience. Human trials show meaningful improvements in testosterone levels, cortisol balance, strength, and mood.

Phytotherapy Research · 2014 · Henkel RR, et al.

Tongkat Ali as a potential herbal supplement for physically active male and female seniors — a pilot study

In a pilot study, physically active seniors supplementing Tongkat Ali showed increases in free and total testosterone alongside improved muscular force.

Read on PubMed →
The Aging Male ยท 2012 ยท Tambi MI, et al.

Effect of Eurycoma longifolia on testosterone levels in men with late-onset hypogonadism

76% of men with low testosterone returned to normal levels after 1 month of Tongkat Ali supplementation.

Read on PubMed โ†’
Journal of the International Society of Sports Nutrition ยท 2013 ยท Talbott SM, et al.

Stress hormones and psychological mood state in moderately stressed humans

Tongkat Ali supplementation reduced cortisol by 16% and improved tension, anger, and confusion scores vs placebo.

Read on PubMed โ†’

๐Ÿต Reishi Mushroom โ€” Ganoderma lucidum

In: Mushroom Extract Complex โ†’

Reishi has been used in Eastern medicine for over 2,000 years. Modern research confirms its immunomodulatory, anti-inflammatory, and adaptogenic properties through beta-glucans and triterpenes.

Cochrane Database of Systematic Reviews ยท 2016 ยท Jin X, et al.

Ganoderma lucidum (Reishi mushroom) and immune function

Reishi significantly enhanced immune function in patients and improved quality of life when used alongside conventional treatment.

Read on PubMed โ†’
Journal of Medicinal Food · 2005 · Tang W, et al.

A randomized, double-blind and placebo-controlled study of a Ganoderma lucidum polysaccharide extract in neurasthenia

In a randomised, double-blind, placebo-controlled study, a Reishi polysaccharide extract significantly reduced fatigue and improved sense of wellbeing versus placebo.

Read on PubMed →

๐ŸŒฑ Ashwagandha — Withania somnifera

In: Shilajit Adaptogen Complex →

One of the most heavily studied adaptogens in Ayurvedic tradition. Randomised, placebo-controlled trials link standardised root extract to lower perceived stress and reduced serum cortisol.

Explore (New York) · 2024 · Arumugam V, et al.

Effects of Ashwagandha (Withania somnifera) on stress and anxiety: A systematic review and meta-analysis

Pooling randomised controlled trials, ashwagandha supplementation was associated with significant reductions in stress and anxiety scores compared with placebo.

Read on PubMed →
Medicine (Baltimore) · 2019 · Lopresti AL, et al.

An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract

In a 60-day randomised, double-blind, placebo-controlled study, participants taking ashwagandha reported lower perceived stress and showed reduced morning cortisol.

Read on PubMed →
Journal of Evidence-Based Complementary & Alternative Medicine · 2017 · Choudhary D, et al.

Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract

Adults under chronic stress taking ashwagandha root extract showed reduced serum cortisol and improved measures of stress-related eating versus placebo.

Read on PubMed →

๐Ÿ„ Cordyceps — Cordyceps sinensis

In: Mushroom Extract Complex · Libido Support Strips →

A high-altitude fungus used for centuries as a stamina tonic. Human trials have measured its effect on oxygen utilisation and exercise capacity — with the clearest signal in older adults. Results in trained younger athletes have been mixed, and we'd rather say so.

Journal of Alternative and Complementary Medicine · 2010 · Chen S, et al.

Effect of Cs-4 (Cordyceps sinensis) on exercise performance in healthy older subjects: a double-blind, placebo-controlled trial

Healthy older adults taking Cs-4 for 12 weeks improved metabolic and ventilatory threshold — a marker of exercise capacity — compared with placebo.

Read on PubMed →

โšก Caffeine + L-Theanine — Camellia sinensis

In: Energy Strips →

L-theanine, the calming amino acid in green tea, pairs with caffeine to sharpen attention while blunting the jittery edge caffeine brings on its own. It is one of the best-supported combinations in the cognitive literature.

Nutritional Neuroscience · 2008 · Owen GN, et al.

The combined effects of L-theanine and caffeine on cognitive performance and mood

L-theanine with caffeine improved speed and accuracy on attention-switching tasks and reduced susceptibility to distraction, compared with placebo.

Read on PubMed →
Nutritional Neuroscience · 2010 · Giesbrecht T, et al.

The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness

The combination improved accuracy on demanding cognitive tasks, increased self-reported alertness and reduced reported tiredness.

Read on PubMed →

๐ŸŒ™ Melatonin + Valerian — Valeriana officinalis

In: Sleep Strips →

Melatonin is the hormone that tells your body it's night. Meta-analyses of randomised trials show it helps people fall asleep faster and rate their sleep as better. Valerian root is a traditional botanical with a smaller but real evidence base.

PLOS ONE · 2013 · Ferracioli-Oda E, et al.

Meta-analysis: melatonin for the treatment of primary sleep disorders

Pooling 19 randomised trials, melatonin significantly reduced the time taken to fall asleep, increased total sleep time and improved overall sleep quality.

Read on PubMed →
Journal of Neurology · 2022 · Fatemeh G, et al.

Effect of melatonin supplementation on sleep quality: a systematic review and meta-analysis of randomized controlled trials

Across randomised controlled trials, melatonin supplementation significantly improved sleep-quality scores compared with placebo.

Read on PubMed →
Journal of Evidence-Based Integrative Medicine · 2020 · Shinjyo N, et al.

Valerian Root in Treating Sleep Problems and Associated Disorders — A Systematic Review and Meta-Analysis

A meta-analysis of 60 studies found valerian may improve subjective sleep quality, with the most consistent effects where standardised whole-root extracts were used.

Read on PubMed →

๐ŸŒฟ Curcumin + Amla — Curcuma longa · Emblica officinalis

In: Hangover Strips →

Curcumin, the active compound in turmeric, is among the most-studied botanicals in modern science — with over a hundred randomised trials examining its antioxidant and inflammatory-balance effects. Amla is an Ayurvedic fruit prized for its polyphenols and vitamin C.

Phytotherapy Research · 2024 · Jafari A, et al.

Curcumin on Human Health: A Comprehensive Systematic Review and Meta-Analysis of 103 Randomized Controlled Trials

Pooling 103 randomised controlled trials, curcumin supplementation was associated with improvements across multiple markers of oxidative stress and inflammatory balance.

Read on PubMed →
International Journal of Molecular Sciences · 2023 · Panknin TM, et al.

Curcumin Supplementation and Human Disease: A Scoping Review of Clinical Trials

A scoping review mapping the breadth of human curcumin trials, and the formulation strategies used to overcome curcumin's naturally low absorption.

Read on PubMed →
American Journal of Chinese Medicine · 2009 · Chen TS, et al.

Supplementation of Emblica officinalis (Amla) extract reduces oxidative stress in uremic patients

Amla extract supplementation significantly reduced markers of oxidative stress in a clinical population.

Read on PubMed →

๐Ÿ”ฅ L-Carnitine + MCT — L-Carnitine · Medium-chain triglycerides

In: Fat Burner with MCT →

L-Carnitine shuttles fatty acids into the mitochondria to be burned for fuel. MCTs are fats absorbed and oxidised faster than the long-chain fats in most diets. Both have been examined in meta-analyses of randomised trials — the effects are real but modest, and they work alongside diet and training, not instead of them.

Clinical Nutrition ESPEN · 2020 · Talenezhad N, et al.

Effects of l-carnitine supplementation on weight loss and body composition: A systematic review and meta-analysis of 37 randomized controlled clinical trials

Across 37 randomised controlled trials, L-carnitine supplementation was associated with significant reductions in body weight and fat mass.

Read on PubMed →
Obesity Reviews · 2016 · Pooyandjoo M, et al.

The effect of (L-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials

Pooled randomised trials found adults receiving L-carnitine lost significantly more weight than control groups.

Read on PubMed →
Journal of the Academy of Nutrition and Dietetics · 2015 · Mumme K, et al.

Effects of medium-chain triglycerides on weight loss and body composition: a meta-analysis of randomized controlled trials

Replacing long-chain fats with medium-chain triglycerides produced small but statistically significant reductions in body weight and fat mass versus controls.

Read on PubMed →

๐Ÿ’ง Hyaluronic Acid — Sodium hyaluronate

In: Hyaluronic Acid Serum →

Hyaluronic acid holds many times its own weight in water. Molecular weight changes how it behaves — larger molecules hold moisture at the surface, smaller ones travel deeper — which is exactly why a serious formula uses several weights at once rather than one.

Dermatologic Therapy · 2022 · Bravo B, et al.

Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence

A review of the clinical evidence for topical hyaluronic acid, reporting improvements in skin hydration, elasticity and the appearance of fine lines.

Read on PubMed →
Archives of Dermatological Research · 2024 · Muhammad P, et al.

Effectiveness of topical hyaluronic acid of different molecular weights in xerosis cutis treatment in elderly: a double-blind, randomized controlled trial

A double-blind randomised controlled trial comparing hyaluronic acid molecular weights for dry skin — supporting the case for formulating with more than one weight.

Read on PubMed →

๐ŸŒŠ Dead Sea Minerals — Magnesium-rich mineral salts

In: Dead Sea Mud →

Dead Sea mud is unusually rich in magnesium, calcium and potassium salts. Controlled research on magnesium-rich Dead Sea salt has measured genuine changes in skin barrier function and hydration — not just a spa-day feeling.

International Journal of Dermatology · 2005 · Proksch E, et al.

Bathing in a magnesium-rich Dead Sea salt solution improves skin barrier function, enhances skin hydration, and reduces inflammation in atopic dry skin

A controlled study found magnesium-rich Dead Sea salt improved skin barrier function and hydration, and reduced roughness and redness, compared with tap water.

Read on PubMed →
Magnesium Research · 2016 · Chandrasekaran NC, et al.

Permeation of topically applied Magnesium ions through human skin is facilitated by hair follicles

Demonstrated that magnesium ions applied to the skin can permeate the skin barrier, with hair follicles acting as the primary route of entry.

Read on PubMed →